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Article

A novel mutation in the GATA4 gene in patients with Tetralogy of Fallot.

Human mutation - 1 Mar 2006

Nemer Georges, Fadlalah Fatimah, Usta Julnar, Nemer Mona, Dbaibo Ghassan, Obeid Mounir, Bitar Fadi

Abstract excerpt

In vertebrates, heart formation which integrates different structures and cell types is a complex process that involves a network of genes regulated by transcription factors. Proper spatiotemporal expression of these factors ensure the highly needed tight control of each step in organogenesis. A mistake at any step from cell-commitment to valve formation will have a major impact on heart morphogenesis and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16470721
DOI: 10.1002/humu.9410

Genes

GATA4
ZFPM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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