Article

Clinical genetic risk variants inform a functional protein interaction network for tetralogy of Fallot

2021-02-19

Abstract excerpt

<h4>Background</h4> Tetralogy of Fallot (TOF), the most common cyanotic heart defect in newborns, has evidence of multiple genetic contributing factors. Identifying variants that are clinically relevant is essential to understand patient-specific disease susceptibility and outcomes, and could contribute to delineating pathomechanisms. <h4>Methods and Results</h4> We used a clinically-driven strategy and current gu...

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Literature Corpus work: 3919a941-f368-5ccd-ad79-cddc4b095c7e
DOI: 10.1101/2021.02.17.21251707

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