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Article

Cyclosporin-A does not affect skeletal muscle mass during disuse and recovery.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Feb 2006

Aoki M S, Miyabara E H, Soares A G, Salvini T F, Moriscot A S

Abstract excerpt

Cyclosporin-A (CsA) is an immunosuppressive drug that acts as an inhibitor of calcineurin, a calcium phosphatase that has been suggested to play a role in skeletal muscle hypertrophy. The aim of the present study was to determine the effect of CsA administration (25 mg kg(-1) day(-1)) on skeletal muscle mass and phenotype during disuse and recovery. Male Wistar rats received vehicle (N = 8) or CsA (N = 8) during...

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Identifiers

PMID: 16470312
DOI: 10.1590/s0100-879x2006000200011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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