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Article

Interaction of chronic creatine depletion and muscle unloading: effects on postural locomotor muscles.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Sept 1994

Adams G R, Haddad F, Baldwin K M

Abstract excerpt

In some rodent skeletal muscles, hindlimb non-weight-bearing activity induces a shift in the expression of myosin heavy chains (MHCs) that favors the type II isoforms at the expense of type I. Chemically induced chronic creatine depletion results in isomyosin shifts favoring expression of type I MHCs. In this study, creatine depletion was induced separately and in combination with non-weight-bearing activity to...

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PMID: 7836122
DOI: 10.1152/jappl.1994.77.3.1198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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