Article
Contractile properties, structure and fiber phenotype of intact and regenerating slow-twitch muscles of mice treated with cyclosporin A.
Cell and tissue research - 1 Apr 2002
Irintchev Andrey, Zweyer Margit, Cooper Racquel N, Butler-Browne Gillian S, Wernig Anton
Abstract excerpt
We have studied the contractile properties, structure, fiber-type composition, and myosin heavy chain (MyHC) expression pattern of regenerating and intact soleus muscles of adult CBA/J mice treated with cyclosporin A (CsA) or vehicle solutions (Cremophor, saline). A comparison of muscles after 4-7 weeks drug application with those receiving vehicle showed that the isometric contractile force of intact...
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