Article
Mild folate deficiency induces a proatherosclerotic phenotype in endothelial cells.
Atherosclerosis - 1 Nov 2006
Brown Karen S, Huang Yuehua, Lu Zhi-Yong, Jian Wenying, Blair Ian A, Whitehead Alexander S
Abstract excerpt
Low folate/high homocysteine (Hcy) is an established risk marker for cardiovascular disease (CVD). Some in vivo studies suggest low folate may independently contribute to CVD. To study the effects of mild folate deficiency on endothelial function, we adapted the EA.hy 926 endothelial cell line to...
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