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Article

Inactivation of the fibronectin-binding adhesin gene bbk32 significantly attenuates the infectivity potential of Borrelia burgdorferi.

Molecular microbiology - 1 Mar 2006

Seshu J, Esteve-Gassent M Dolores, Labandeira-Rey Maria, Kim Jung Hwa, Trzeciakowski Jerome P, Höök Magnus, Skare Jonathan T

Abstract excerpt

Borrelia burgdorferi, the aetiological agent of Lyme disease, utilizes multiple adhesins to interact with both the arthropod vector and mammalian hosts it colonizes. One such adhesive molecule is a surface-exposed fibronectin-binding lipoprotein, designated BBK32. Previous characterization of BBK32-mediated fibronectin binding has been limited to biochemical analyses due to the difficulty in mutagenizing...

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Identifiers

PMID: 16468997
DOI: 10.1111/j.1365-2958.2005.05042.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Inactivation of the fibronectin-binding adhesin gene bbk32 significantly attenuates the infectivity potential of Borrelia burgdorferi.PMID 16468997Read ↗

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