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Article

The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing.

The Journal of biological chemistry - 3 Oct 1997

Heinemeyer W, Fischer M, Krimmer T, Stachon U, Wolf D H

Abstract excerpt

The 26 S proteasome is the central protease involved in ubiquitin-mediated protein degradation and fulfills vital regulatory functions in eukaryotes. The proteolytic core of the complex is the 20 S proteasome, a cylindrical particle with two outer rings each made of 7 different alpha-type subunits and two inner rings made of 7 different beta-type subunits. In the archaebacterial 20 S proteasome ancestor...

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PMID: 9312134
DOI: 10.1074/jbc.272.40.25200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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