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Article

CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD.

Clinica chimica acta; international journal of clinical chemistry - 2 Apr 2010

Vibhuti Arpana, Arif Ehtesham, Mishra Aastha, Deepak Desh, Singh Bhawani, Rahman Irfan, Mohammad Ghulam, Pasha M A Qadar

Abstract excerpt

BACKGROUND: The genetic susceptibility to chronic obstructive pulmonary disease (COPD) depends on detoxification and antioxidant enzymes, which detoxify cigarette smoke reactive components that, otherwise, generate oxidative stress. METHODS: In a case-control study of 346 subjects with and without COPD, we examined the polymorphisms 462Ile/Val, 3801T/C of CYP1A1, -3860G/A of CYP1A2 and -930A/G, 242C/T of CYBA...

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Source

Identifiers

PMID: 20080081
DOI: 10.1016/j.cca.2009.12.018

Genes

CYBA
CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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