Article
Swimming behaviour and post-swimming activity in Vitamin D receptor knockout mice.
Brain research bulletin - 15 Mar 2006
Burne Thomas H J, Johnston Amy N B, McGrath John J, Mackay-Sim Alan
Abstract excerpt
Animal experiments have shown that Vitamin D plays a role in both brain development and adult brain function. The adult Vitamin D receptor null mutant mouse (VDR -/-) is reported to be less active and more anxious than wild-type litter mate controls and to have poor swimming ability. However, an "anxious" behavioural phenotype is inferred from differences in locomotor behaviour. This is a general problem in...
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