Article
A maximum likelihood method for studying gene-environment interactions under conditional independence of genotype and exposure.
Statistics in medicine - 30 Sept 2006
Cheng K F
Abstract excerpt
Given the biomedical interest in gene-environment interactions along with the difficulties inherent in gathering genetic data from controls, epidemiologists need methodologies that can increase precision of estimating interactions while minimizing the genotyping of controls. To achieve this purpose, many epidemiologists suggested that one can use case-only design. In this paper, we present a maximum likelihood...
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