Article
The impact of iron overload and genotype on gonadal function in women with thalassaemia major.
Pediatric endocrinology reviews : PER - 1 Dec 2004
Skordis Nicos, Gourni Maritsa, Kanaris Constantinos, Toumba Meropi, Kleanthous Marina, Karatzia Ntina, Pavlides Nicos, Angastiniotis Michael
Abstract excerpt
OBJECTIVE: The purpose of this study is to evaluate the impact of chronic iron overload and genotype on gonadal function in women with thalassaemia major. PATIENTS AND METHODS: The study population consists of 101 women aged 15-48 years who were treated between 1981 and 1999. These women were divided into two groups according to their genotype: [A=no modifying genetic factor and B=presence of modifying factors],...
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