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Article

Hypogonadotropic hypogonadism and hematologic phenotype in patients with transfusion-dependent beta-thalassemia.

Journal of pediatric hematology/oncology - 1 Nov 2003

Chern Jimmy P S, Lin Kai-Hsin, Tsai Wen-Yu, Wang Shih-Chung, Lu Meng-Yao, Lin Dong-Tsamn, Lin Kuo-Sin, Lo Su Heuy

Abstract excerpt

OBJECTIVE: To determine the prevalence and risk factors of hypogonadotropic hypogonadism in transfusion-dependent patients with thalassemia. PATIENTS AND METHODS: The authors examined 29 patients with thalassemia major aged 15 years or older. Luteinizing hormone-releasing hormone tests were performed and beta-thalassemia mutations were analyzed by direct sequencing. RESULTS: The prevalence of hypogonadotropic...

Topics

Adolescent
Adult
Blood Transfusion
Female
Genotype
Gonadotropin-Releasing Hormone
Gonadotropins
Humans
Hypogonadism
Male
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

beta-Thalassemia

Source

Identifiers

PMID: 14608198
DOI: 10.1097/00043426-200311000-00011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-14608198-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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