Article
Incidence of endocrine complications and clinical disease severity related to genotype analysis and iron overload in patients with beta-thalassaemia.
European journal of haematology - 1 Aug 1997
Jensen C E, Tuck S M, Old J, Morris R W, Yardumian A, De Sanctis V, Hoffbrand A V, Wonke B
Abstract excerpt
The incidence of endocrine dysfunction in relation to the detailed genotype of beta-thalassaemia is investigated in this study. In addition, the association of genotype to specific clinical features of beta-thalassaemia is examined, together with the relationship between serum ferritin levels and endocrine complications. Ninety-seven patients were included, all with transfusion dependent beta-thalassaemia....
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