Article
The impact of genotype on endocrine complications in thalassaemia major.
European journal of haematology - 1 Aug 2006
Skordis Nicos, Michaelidou Monica, Savva Savvas C, Ioannou Yiannis, Rousounides Andreas, Kleanthous Marina, Skordos George, Christou Soteroulla
Abstract excerpt
BACKGROUND: The clinical severity in thalassaemia major (TM) depends on the underlying mutations of the beta-globin gene and the degree of iron overload. OBJECTIVE: The aim of the study was to investigate the impact of genotype on the development of endocrine complications in TM in our center. SUBJECTS AND METHODS: 126 (62 males, 64 females) thalassaemic patients of Greek Cypriot origin with a mean age of 31.2...
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