Article
The impact of hemochromatosis mutations and transferrin genotype on gonadotropin serum levels in infertile men.
Fertility and sterility - 1 May 2009
Buretić-Tomljanović Alena, Vlastelić Ivan, Radojcić Badovinac Andelka, Starcević-Cizmarević Nada, Nadalin Sergej, Ristić Smiljana
Abstract excerpt
OBJECTIVE: To address the possibility that HFE mutations and TF gene polymorphism cause dysfunction of spermatogenesis and/or the hypothalamic-pituitary-gonadal axis via contribution to long-term iron overload in the testes and brain. DESIGN: Case-control and association study. SETTING: Clinic of obstetrics and gynecology and university-based research laboratory. PATIENT(S): 127 infertile men (including 97 with...
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