Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Melatonin receptor (MT1) knockout mice display depression-like behaviors and deficits in sensorimotor gating.

Brain research bulletin - 15 Feb 2006

Weil Zachary M, Hotchkiss Andrew K, Gatien Michelle L, Pieke-Dahl Sandra, Nelson Randy J

Abstract excerpt

Although critical for transducing seasonal information, melatonin has also been implicated in several physiological systems, as well as the regulation of behavioral and cognitive processes. Therefore, we investigated the neurobehavioral effects of mice missing the type 1 melatonin receptor (MT1). Male and female MT1 knockout (MT1-/-) and wild-type (WT) mice were tested in the acoustic startle/prepulse inhibition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Animal
Share to Brain
Share to Brain Chemistry

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Depressive Disorder

Share to Melatonin

Share to Reflex, Startle

Share to Sensation Disorders

Share to Sex Characteristics

Source

Identifiers

PMID: 16459197
DOI: 10.1016/j.brainresbull.2005.09.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Melatonin receptor (MT1) knockout mice display depression-like behaviors and deficits in sensorimotor gating.PMID 16459197Read ↗

Targeted disruption of the mouse Mel(1b) melatonin receptor.Semantic proximity Read ↗

Thyrotropin-releasing hormone receptor 1-deficient mice display increased depression and anxiety-like behavior.Semantic proximity Read ↗

Distinct behavioral phenotypes in male mice lacking the thyroid hormone receptor α1 or β isoforms.Semantic proximity Read ↗

Melatonin Receptor Genes in VertebratesSemantic proximity Read ↗

Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulbSemantic proximity Read ↗

Gene expression profile associated with Asmt knockout-induced depression-like behaviors and exercise effects in mouse hypothalamusSemantic proximity Read ↗

Sex-dependent adaptive changes in serotonin-1A autoreceptor function and anxiety in Deaf1-deficient mice.Semantic proximity Read ↗

A review of the melatonin functions in zebrafish physiologySemantic proximity Read ↗

A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female mice.Semantic proximity Read ↗

A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female miceSemantic proximity Read ↗

Meis1: effects on motor phenotypes and the sensorimotor system in mice.Semantic proximity Read ↗

5-HT1A receptor and 5-HT1B receptor knockout mice in stress and anxiety paradigms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.