Article
Exploring the interaction between the protein kinase A catalytic subunit and caveolin-1 scaffolding domain with shotgun scanning, oligomer complementation, NMR, and docking.
Protein science : a publication of the Protein Society - 1 Mar 2006
Levin Aron M, Coroneus John G, Cocco Melanie J, Weiss Gregory A
Abstract excerpt
The techniques of phage-displayed homolog shotgun scanning, oligomer complementation, NMR secondary structure analysis, and computational docking provide a complementary suite of tools for dissecting protein-protein interactions. Focusing these tools on the interaction between the catalytic sub-unit of protein kinase A (PKAcat) and caveolin-1 scaffolding domain (CSD) reveals the first structural model for the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.