Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accuracy of haplotype estimation in a region of low linkage disequilibrium.

BMC genetics - 30 Dec 2005

Avery Christy L, Martin Lisa J, Williams Jeff T, North Kari E

Abstract excerpt

We compared the accuracy of haplotype inferences at a 6 Mb region on chromosome 7 where significant linkage between a brain oscillation phenotype and a cholinergic muscarinic receptor gene was previously reported. Individual haplotype assignments and haplotype frequencies were estimated using 5, 10, and 14 consecutive Illumina single-nucleotide polymorphisms (SNPs) within the 1-LOD unit support interval of the...

Topics

Family
Genetic Loci
Genetics, Population
Haplotypes
Humans
Linkage Disequilibrium
Oligonucleotide Array Sequence Analysis
Polymorphism, Single Nucleotide
Quantitative Trait Loci

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 16451695
DOI: 10.1186/1471-2156-6-S1-S80
PMCID: PMC1866700

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16451695-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Accuracy of haplotype estimation in a region of low linkage disequilibrium.PMID 16451695Read ↗

Accounting for haplotype phase uncertainty in linkage disequilibrium estimation.Semantic proximity Read ↗

Accounting for linkage disequilibrium among markers in linkage analysis: impact of haplotype frequency estimation and molecular haplotypes for a gene in a candidate region for Alzheimer's disease.Semantic proximity Read ↗

Genome scan linkage analysis comparing microsatellites and single-nucleotide polymorphisms markers for two measures of alcoholism in chromosomes 1, 4, and 7.Semantic proximity Read ↗

Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data.Semantic proximity Read ↗

Single-nucleotide polymorphism versus microsatellite markers in a combined linkage and segregation analysis of a quantitative trait.Semantic proximity Read ↗

Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus.Semantic proximity Read ↗

Haplotype frequency estimation error analysis in the presence of missing genotype data.Semantic proximity Read ↗

Comparison of the accuracy of methods of computational haplotype inference using a large empirical dataset.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.