Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus.

doi:10.1073/pnas.052716399

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Article

Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus.

Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2002

Porjesz Bernice, Almasy Laura, Edenberg Howard J, Wang Kongming, Chorlian David B, Foroud Tatiana, Goate Alison, Rice John P, O'Connor Sean J, Rohrbaugh John, Kuperman Samuel, Bauer Lance O, Crowe Raymond R, Schuckit Marc A, Hesselbrock Victor, Conneally P Michael, Tischfield Jay A, Li Ting-Kai, Reich Theodore, Begleiter Henri

Abstract excerpt

Human brain oscillations represent important features of information processing and are highly heritable. A common feature of beta oscillations (13-28 Hz) is the critical involvement of networks of inhibitory interneurons as pacemakers, gated by gamma-aminobutyric acid type A (GABA(A)) action. Advances in molecular and statistical genetics permit examination of quantitative traits such as the beta frequency of...

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PMID: 11891318
DOI: 10.1073/pnas.052716399
PMCID: PMC122592

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