Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Susceptibility to mycobacterial infections due to interferon-gamma and interleukin-12 pathway defects.

Allergy and asthma proceedings - 1 Jan 2000

Tran Dat Q

Abstract excerpt

A case of interferon-gamma (IFN-gamma)/interleukin-12 (IL-12) pathway defect is presented. Pathophysiology, clinical characteristics, diagnostic test, and case management are reviewed. Clinical Pearls and Pitfalls include: (1) A high probability of a defect in the IFN-gamma/IL-12 cascade exists in patients with disseminated or recurrent infection due to poorly pathogenic mycobacteria or systemic infections caused...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Interferon gamma Receptor
Share to Interleukin-12

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mycobacterium avium-intracellulare Infection

Share to Osteomyelitis

Share to Receptors, Interferon

Share to Recurrence

Share to Salmonella Infections

Source

Identifiers

PMID: 16450579

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Susceptibility to mycobacterial infections due to interferon-gamma and interleukin-12 pathway defects.PMID 16450579Read ↗

What We Have Here Is a Failure to Communicate: Interleukin-12 / Interferon-gamma Axis Defects and Mendelian Susceptibility to Mycobacterial Disease.Semantic proximity Read ↗

Defects in the interferon-gamma and interleukin-12 pathways.Semantic proximity Read ↗

IL12Rβ1 defect presenting with massive intra-abdominal lymphadenopathy due to Mycobacterium intracellulare infection.Semantic proximity Read ↗

[Mendelian susceptibility to mycobacterial disease: defects in the IL-12/IFNgamma pathway].Semantic proximity Read ↗

Interferon-gamma and interleukin-12 pathway defects and human disease.Semantic proximity Read ↗

Laboratory evaluation of the IFN-γ circuit for the molecular diagnosis of Mendelian susceptibility to mycobacterial disease.Semantic proximity Read ↗

Diagnosis of defects in the type 1 cytokine pathway.Semantic proximity Read ↗

Innate defects of the IL-12/IFN-γ axis in susceptibility to infections by mycobacteria and salmonella.Semantic proximity Read ↗

Disseminated Salmonellosis in a child with IL12Rß1 deficiency – Case report and review of literature.Semantic proximity Read ↗

Human genetics of intracellular infectious diseases: molecular and cellular immunity against mycobacteria and salmonellae.Semantic proximity Read ↗

Genetic deficiencies of innate immune signalling in human infectious disease.Semantic proximity Read ↗

Human host genetic factors in mycobacterial and Salmonella infection: lessons from single gene disorders in IL-12/IL-23-dependent signaling that affect innate and adaptive immunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.