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Article

Apolipoprotein E polymorphism affects carotid artery atherosclerosis in smoking hypertensive men.

Journal of hypertension - 1 Dec 2002

Karvonen Jarkko, Kauma Heikki, Kervinen Kari, Ukkola Olavi, Rantala Maire, Päivänsalo Markku, Savolainen Markku J, Kesäniemi Y Antero

Abstract excerpt

OBJECTIVE: Smoking is a risk factor for increased carotid artery intima-media thickness (IMT). The apolipoprotein E (apoE) 4 allele has been associated with cardiovascular diseases, but the role of apoE in regard to intima-media thickness (IMT) has remained controversial. The objective was to investigate whether there is some gene-environment interaction between smoking and apoE polymorphism. DESIGN...

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Identifiers

PMID: 12473860
DOI: 10.1097/00004872-200212000-00015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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