Article
Polymorphisms of apolipoprotein E and angiotensin-converting enzyme genes and carotid atherosclerosis in heavy drinkers.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Bednarska-Makaruk Małgorzata, Rodo Maria, Markuszewski Cezary, Rozenfeld Anna, Swiderska Malgorzata, Habrat Bogusław, Wehr Hanna
Abstract excerpt
AIMS: To investigate the influence of apolipoprotein E (APOE) and angiotensin-converting enzyme (ACE) gene polymorphisms on carotid artery atherosclerosis in alcoholism. METHODS: Polymorphism of both genes was identified by DNA analysis in 130 male alcohol-dependent patients. Intima-media thickness (IMT) was measured ultrasonographically. RESULTS: Multivariate regression analysis showed that of all the known risk...
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