Polymorphisms of apolipoprotein E and angiotensin-converting enzyme genes and carotid atherosclerosis in heavy drinkers.

doi:10.1093/alcalc/agh157

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Article

Polymorphisms of apolipoprotein E and angiotensin-converting enzyme genes and carotid atherosclerosis in heavy drinkers.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000

Bednarska-Makaruk Małgorzata, Rodo Maria, Markuszewski Cezary, Rozenfeld Anna, Swiderska Malgorzata, Habrat Bogusław, Wehr Hanna

Abstract excerpt

AIMS: To investigate the influence of apolipoprotein E (APOE) and angiotensin-converting enzyme (ACE) gene polymorphisms on carotid artery atherosclerosis in alcoholism. METHODS: Polymorphism of both genes was identified by DNA analysis in 130 male alcohol-dependent patients. Intima-media thickness (IMT) was measured ultrasonographically. RESULTS: Multivariate regression analysis showed that of all the known risk...

Topics

Adult
Aged
Alcohol Drinking
Alcoholism
Apolipoproteins E
Carotid Arteries
Carotid Artery Diseases
Genetic Predisposition to Disease
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Peptidyl-Dipeptidase A

Polymorphism, Genetic

Psychiatric Status Rating Scales

Risk Factors

Ultrasonography

Source

Open in PubMed

Identifiers

PMID: 15809232
DOI: 10.1093/alcalc/agh157

Genes

ACE
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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