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Article

ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity.

Diabetes - 1 Feb 2006

Bouatia-Naji Nabila, Meyre David, Lobbens Stéphane, Séron Karin, Fumeron Frédéric, Balkau Beverley, Heude Barbara, Jouret Béatrice, Scherer Philipp E, Dina Christian, Weill Jacques, Froguel Philippe

Abstract excerpt

Common single nucleotide polymorphisms (SNPs) in the ACDC adiponectin encoding gene have been associated with insulin resistance and type 2 diabetes in several populations. Here, we investigate the role of SNPs -11,377C > G, -11,391G > A, +45T > G, and +276G > T in 2,579 French Caucasians (1,229 morbidly obese and 1,350 control subjects). We found an association between severe forms of obesity and -11,377C (odds...

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Identifiers

PMID: 16443793
DOI: 10.2337/diabetes.55.02.06.db05-0971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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