Article
The SNP276G>T polymorphism in the adiponectin (ACDC) gene is more strongly associated with insulin resistance and cardiovascular disease risk than SNP45T>G in nonobese/nondiabetic Korean men independent of abdominal adiposity and circulating plasma adiponectin.
Metabolism: clinical and experimental - 1 Jan 2006
Jang Yangsoo, Lee Jong Ho, Kim Oh Yoen, Koh Soo Jeong, Chae Jey Sook, Woo Jin Hee, Cho Hongkeun, Lee Jong Eun, Ordovas Jose M
Abstract excerpt
This study aimed to determine whether polymorphisms of the adiponectin (ACDC) gene independently contribute to insulin resistance (IR) and other cardiovascular disease (CVD) risk factors in nonobese, nondiabetic Korean men after adjusting for major environmental factors that influence IR. Among the 7 ACDC single-nucleotide polymorphisms (SNPs;C-11377G, T45G, G276T, H241P, Y111H, G90S, and R221S) prescreened in 48...
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