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Article

The promoter region of the adiponectin gene is a determinant in modulating insulin sensitivity in childhood obesity.

Obesity (Silver Spring, Md.) - 1 Sept 2006

Petrone Antonio, Zavarella Sara, Caiazzo Assunta, Leto Gaetano, Spoletini Marialuisa, Potenziani Stella, Osborn John, Vania Andrea, Buzzetti Raffaella

Abstract excerpt

We investigated the association of the -11,391G>A, -11,377G>C, +45T>G, and +276G>T adiponectin single-nucleotide polymorphisms (SNPs) and expected haplotypes with the insulin resistance (IR) state in overweight/obese children; by using the haplotype background analysis, we also assessed the effect of each SNP independently. GG genotype at the -11,391 locus was associated with higher fasting insulin levels and...

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Source

Identifiers

PMID: 17030959
DOI: 10.1038/oby.2006.172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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