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A genetic analysis identifies a haplotype at adiponectin locus: Association with obesity and type 2 diabetes.

Scientific reports - 19 Feb 2020

Palit Sayantani Pramanik, Patel Roma, Jadeja Shahnawaz D, Rathwa Nirali, Mahajan Ankit, Ramachandran A V, Dhar Manoj K, Sharma Swarkar, Begum Rasheedunnisa

Abstract excerpt

Adiponectin is a prime determinant of the status of insulin resistance. Association studies between adiponectin (ADIPOQ) gene single nucleotide polymorphisms (SNPs) and metabolic diseases have been reported earlier. However, results are ambiguous due to apparent contradictions. Hence, we investigated (1) the association between ADIPOQ SNPs: -11377C/G, +10211T/G, +45T/G and +276G/T for the risk towards type 2...

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Adiponectin
Diabetes Mellitus, Type 2
Genetic Association Studies
Genetic Loci
India

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

Molecular Weight

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Identifiers

PMID: 32076038
DOI: 10.1038/s41598-020-59845-z
PMCID: PMC7031532

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