Article
Cell therapy of pain: Characterization of human fetal chromaffin cells at early adrenal medulla development.
Experimental neurology - 1 Apr 2006
Zhou H, Aziza J, Sol J C, Courtade-Saïdi M, Chatelin S, Evra C, Parant O, Lazorthes Y, Jozan S
Abstract excerpt
Adult adrenal chromaffin cells are being utilized for therapeutic transplantation. With the prospect of using fetal chromaffin cells in pain therapy, we studied their phenotype, proliferative power, function, and growth in vitro and in situ in order to determine the optimal time for implantation. Between 7 and 10 gestational weeks (GW), we isolated, in vitro, two types of chromaffin cells with a noradrenergic...
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