Article
Differentiation to a neuronal phenotype in bovine chromaffin cells is repressed by protein kinase C and is not dependent on c-fos oncoproteins.
DNA and cell biology - 1 Jun 1990
Demeneix B A, Kley N, Loeffler J P
Abstract excerpt
We investigated the intracellular signals underlying the neurotrophic response of adult bovine chromaffin cells to histamine and basic fibroblast growth factor (bFGF). Histamine produced significant neurite outgrowth within 48 hr, whereas the response to bFGF developed after 1 week. H7, a protein...
Topics
- Adrenal Medulla
- Animals
- Cattle
- Cell Differentiation
- Enzyme Activation
- Fibroblast Growth Factors
- Histamine
- In Vitro Techniques
- Neurons
- Phenotype
- Protein Kinase C
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-fos
- Signal Transduction
- Tetradecanoylphorbol Acetate