Article
Generation of neuroendocrine chromaffin cells from sympathoadrenal progenitors: beyond the glucocorticoid hypothesis.
Annals of the New York Academy of Sciences - 1 Oct 2002
Huber Katrin, Combs Stephanie, Ernsberger Uwe, Kalcheim Chaya, Unsicker Klaus
Abstract excerpt
The developmental diversification of neural crest-derived sympathoadrenal (SA) progenitor cells into neuroendocrine adrenal chromaffin cells and sympathetic neurons has been thought to be largely understood. Based on two decades of in vitro studies with isolated SA progenitor and chromaffin cells, it was widely assumed that chromaffin cell development crucially depends on glucocorticoid hormones provided by...
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