Article
A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro.
Experimental brain research - 1 Jan 1993
Barker R, Dunnett S, Fawcett J
Abstract excerpt
Rat chromaffin cells display phenotypic plasticity postnatally. In the presence of glucocorticoids, they retain a chromaffin cell phenotype, whilst in the presence of nerve growth factor and the absence of glucocorticoids they adopt a sympathetic neuronal phenotype. The tachykinins have some of the characteristics of a neurotrophic factor and are present in the form of a substance P afferent input in the rat...
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