Article
Early fetal acquisition of the chromaffin and neuronal immunophenotype by human adrenal medullary cells. An immunohistological study using monoclonal antibodies to chromogranin A, synaptophysin, tyrosine hydroxylase, and neuronal cytoskeletal proteins.
Experimental neurology - 1 Apr 1990
Molenaar W M, Lee V M, Trojanowski J Q
Abstract excerpt
The development of chromaffin and neuronal features in the adrenal medulla was studied in normal human fetuses with gestational ages (GAs) of 6-34 weeks. Monoclonal antibodies specific for chromogranin A, synaptophysin, and tyrosine hydroxylase; for different subunits and phosphoisoforms of neurofilament (NF) proteins; and for microtubule-associated proteins were applied. Morphologically, two major cell types...
Topics
- Adrenal Medulla
- Antibodies, Monoclonal
- Chromaffin System
- Chromogranin A
- Chromogranins
- Cytoskeletal Proteins
- Humans
- Immunoenzyme Techniques
- Immunohistochemistry
- Intermediate Filament Proteins