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Article

A mutational analysis of the ColE1-encoded cell cycle regulator Rcd confirms its role in plasmid stability.

Plasmid - 1 Jul 2006

Balding Claire, Blaby Ian, Summers David

Abstract excerpt

Multimers of multicopy plasmids cause instability. They arise by homologous recombination and accumulate by over-replication in a process known as the dimer catastrophe. Dimers are resolved to monomers by site-specific recombination systems such as Xer-cer of plasmid ColE1. In addition, the Rcd checkpoint hypothesis proposes that a short transcript (Rcd) coded within ColE1 cer delays the division of...

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Source

Identifiers

PMID: 16442621
DOI: 10.1016/j.plasmid.2005.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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