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Article

ACE gene polymorphisms influence t-PA-induced brain vessel reopening following ischemic stroke.

Neuroscience letters - 8 May 2006

Fernández-Cadenas Israel, Molina Carlos Alberto, Alvarez-Sabín José, Ribó Marc, Penalba Anna, Ortega-Torres Laura, Delgado Pilar, Quintana Manolo, Rosell Anna, Montaner Joan

Abstract excerpt

Angiotensin converting enzyme (ACE) influences vessels tone and the coagulation/fibrinolysis system. The ACE gene I/D polymorphism has been linked with PAI-1 and fibrinogen levels and with Factors VII and X activities. Therefore, we aimed to test whether I/D polymorphism could be related to thrombolysis safety and efficacy. We studied strokes involving the middle cerebral artery (MCA) territory of patients who...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Fibrinolytic Agents

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Source

Identifiers

PMID: 16442232
DOI: 10.1016/j.neulet.2005.12.079

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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