Article
CD40-1C>T polymorphism (rs1883832) is associated with brain vessel reocclusion after fibrinolysis in ischemic stroke.
Pharmacogenomics - 1 Jun 2010
del Río-Espínola Alberto, Fernández-Cadenas Israel, Rubiera Marta, Quintana Manuel, Domingues-Montanari Sophie, Mendióroz Maite, Fernández-Morales Jessica, Giralt Dolors, Molina Carlos A, Alvarez-Sabín José, Montaner Joan
Abstract excerpt
AIMS: To find genetic predictors of reocclusion after successful fibrinolytic therapy during the acute phase of ischemic stroke. PATIENTS & METHODS: This was a case-case prospective study analyzing 236 polymorphisms in a cohort of 222 patients treated with tissue plasminogen activator, from which 16 patients suffered a reocclusion event (7.2%). A predictive scale was generated using independent polymorphisms with...
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