Article
[ApoE genotype influences on efficacy and safety of thrombolytic treatment for ischemic stroke].
Neurologia (Barcelona, Spain) - 1 May 2006
Fernández-Cadenas I, Alvarez Sabín J, Molina C A, Ribó M, Rosell A, Penalba A, Ortega L, Montaner J
Abstract excerpt
INTRODUCTION: Apolipoprotein E has been associated with intracerebral hemorrhages and with neurological outcome of ischemic stroke patients treated with rt-PA. Therefore, we hypothesized that ApoE genotype might influence the appearance of post-tPA hemorrhagic transformation and that the favorable outcome of E2 patients might be due to better rates of recanalization. PATIENTS AND METHODS: We analyzed the ApoE...
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