The I/D polymorphism of the ACE1 gene is not associated with  ischaemic stroke in Spanish individuals.

doi:10.1111/j.1468-1331.2010.03022.x

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Article

The I/D polymorphism of the ACE1 gene is not associated with ischaemic stroke in Spanish individuals.

European journal of neurology - 1 Nov 2010

Domingues-Montanari S, Fernandez-Cadenas I, del Rio-Espinola A, Mendioroz M, Ribo M, Obach V, Marti-Fabregas J, Freijo M, Serena J, Corbeto N, Chacon P, Alvarez-Sabin J, Montaner J

Abstract excerpt

BACKGROUND: The angiotensin-converting enzyme 1 (ACE1) gene has been extensively studied in stroke, yet generating conflicting results. The goal of our study was thus to clarify the influence of the ACE1 on the risk of suffering an ischaemic stroke (IS). METHODS: We genotyped the rs4341 (in linkage disequilibrium with the I/D polymorphism) of the ACE1 gene in 531 patients with IS and 549 healthy controls, and the...

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PMID: 20402757
DOI: 10.1111/j.1468-1331.2010.03022.x

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