Article
The -148 C/T fibrinogen gene polymorphism and fibrinogen levels in ischaemic stroke: a case-control study.
Journal of neurology, neurosurgery, and psychiatry - 1 Jan 2005
van Goor M P J, Gómez-García E B, Leebeek F W G, Brouwers G J, Koudstaal P J, Dippel D W J
Abstract excerpt
BACKGROUND: To determine whether -148 C/T fibrinogen gene promoter polymorphism increases stroke risk by modifying the fibrinogen level. DESIGN: A case-control study of patients with first ever ischaemic stroke, confirmed by computed tomography. METHODS: Venous blood samples were collected for fibrinogen and routine coagulation tests one week after the stroke, and after three months in about half the patients....
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