Article
Androgen effects on hippocampal CA1 spine synapse numbers are retained in Tfm male rats with defective androgen receptors.
Endocrinology - 1 May 2006
MacLusky Neil J, Hajszan Tibor, Johansen Jamie A, Jordan Cynthia L, Leranth Csaba
Abstract excerpt
The effects of estradiol benzoate (EB), dihydrotestosterone (DHT), or the antiandrogen hydroxyflutamide on CA1 pyramidal cell dendritic spine synapses were investigated in adult male rats. To elucidate the contribution of the androgen receptor to the hormone-induced increase in hippocampal CA1 synapses, wild-type males were compared with males expressing the Tfm mutation, which results in synthesis of defective...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.