Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ciliary neurotrophic factor arrests muscle and motoneuron degeneration in androgen-insensitive rats.

Journal of neurobiology - 1 Nov 1995

Forger N G, Wong V, Breedlove S M

Abstract excerpt

Steroid hormones and neurotrophic factors exert profound and widespread effects on the developing nervous system, including regulation of the size, connectivity, and survival of neurons. Androgenic control of the survival of motoneurons in the spinal nucleus of the bulbocavernosus (SNB) of rats has been well documented. We previously found that ciliary neurotrophic factor (CNTF) mimics many effects of androgen on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Linkage
Share to Nerve Growth Factors
Share to Nerve Tissue Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Rats, Sprague-Dawley

Share to Receptors, Androgen

Share to X Chromosome

Source

Identifiers

PMID: 8568516
DOI: 10.1002/neu.480280308

Genes

CNTF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ciliary neurotrophic factor arrests muscle and motoneuron degeneration in androgen-insensitive rats.PMID 8568516Read ↗

Androgen spares androgen-insensitive motoneurons from apoptosis in the spinal nucleus of the bulbocavernosus in rats.Semantic proximity Read ↗

Characterization of the spinal nucleus of the bulbocavernosus neuromuscular system in male mice lacking androgen receptor in the nervous system.Semantic proximity Read ↗

Direct androgenic regulation of calcitonin gene-related peptide expression in motoneurons of rats with mosaic androgen insensitivity.Semantic proximity Read ↗

Prenatal flutamide enhances survival in a myogenic mouse model of spinal bulbar muscular atrophy.Semantic proximity Read ↗

Steroid hormone masculinization of neural structure in rats: a tale of two nuclei.Semantic proximity Read ↗

N-cadherin expression in motoneurons is directly regulated by androgens: a genetic mosaic analysis in rats.Semantic proximity Read ↗

Androgen Action via the Androgen Receptor in Neurons Within the Brain Positively Regulates Muscle Mass in Male Mice.Semantic proximity Read ↗

Neurotoxic effects of androgens in spinal and bulbar muscular atrophySemantic proximity Read ↗

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy.Semantic proximity Read ↗

A cell culture model for androgen effects in motor neurons.Semantic proximity Read ↗

The role of the androgen receptor in CNS masculinization.Semantic proximity Read ↗

Androgen regulates development of the sexually dimorphic gastrin-releasing peptide neuron system in the lumbar spinal cord: evidence from a mouse line lacking androgen receptor in the nervous system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.