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Article

Determination of network of residues that regulate allostery in protein families using sequence analysis.

Protein science : a publication of the Protein Society - 1 Feb 2006

Dima Ruxandra I, Thirumalai D

Abstract excerpt

Allosteric interactions between residues that are spatially apart and well separated in sequence are important in the function of multimeric proteins as well as single-domain proteins. This observation suggests that, among the residues that are involved in long-range communications, mutation at one site should affect interactions at a distant site. By adopting a sequence-based approach, we present an automated...

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Identifiers

PMID: 16434743
DOI: 10.1110/ps.051767306
PMCID: PMC2242462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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