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Article

Harnessing natural diversity to probe metabolic pathways.

PLoS genetics - 1 Dec 2005

Homann Oliver R, Cai Houjian, Becker Jeffrey M, Lindquist Susan L

Abstract excerpt

Analyses of cellular processes in the yeast Saccharomyces cerevisiae rely primarily upon a small number of highly domesticated laboratory strains, leaving the extensive natural genetic diversity of the model organism largely unexplored and unexploited. We asked if this diversity could be used to enrich our understanding of basic biological processes. As a test case, we examined a simple trait: the utilization of...

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PMID: 16429164
DOI: 10.1371/journal.pgen.0010080
PMCID: PMC1342634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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