Article
The sex-specific genetic architecture of quantitative traits in humans.
Nature genetics - 1 Feb 2006
Weiss Lauren A, Pan Lin, Abney Mark, Ober Carole
Abstract excerpt
Mapping genetically complex traits remains one of the greatest challenges in human genetics today. In particular, gene-environment and gene-gene interactions, genetic heterogeneity and incomplete penetrance make thorough genetic dissection of complex traits difficult, if not impossible. Sex could be considered an environmental factor that can modify both penetrance and expressivity of a wide variety of traits....
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