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Article

Unique Transcriptome Signature of <i>Mycobacterium tuberculosis</i> in Pulmonary Tuberculosis

20 Jan 2006

Abstract excerpt

Although tuberculosis remains a substantial global threat, the mechanisms that enable mycobacterial persistence and replication within the human host are ill defined. This study represents the first genome-wide expression analysis of Mycobacterium tuberculosis from clinical lung samples, which has enabled the identification of M. tuberculosis genes actively expressed during pulmonary tuberculosis. To obtain...

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PMID: 16428773
DOI: 10.1128/iai.74.2.1233-1242.2006

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