Article
Virulence of Staphylococcus aureus small colony variants in the Caenorhabditis elegans infection model.
Infection and immunity - 1 Feb 2006
Sifri Costi D, Baresch-Bernal Andrea, Calderwood Stephen B, von Eiff Christof
Abstract excerpt
Small colony variants (SCVs) of Staphylococcus aureus are slow-growing morphological variants that have been implicated in persistent, relapsing, and antibiotic-resistant infections. The altered phenotype of SCVs in most strains has been attributed to defects in electron transport due to mutations in hemin or menadione biosynthesis. The pathogenic capacity of SCVs compared to phenotypically normal strains is...
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