Article
Identification of point mutations in clinical Staphylococcus aureus strains that produce small-colony variants auxotrophic for menadione.
Infection and immunity - 1 Apr 2014
Dean Melissa A, Olsen Randall J, Long S Wesley, Rosato Adriana E, Musser James M
Abstract excerpt
Staphylococcus aureus small-colony variants (SCVs) are implicated in chronic and relapsing infections that are difficult to diagnose and treat. Despite many years of study, the underlying molecular mechanisms and virulence effect of the small-colony phenotype remain incompletely understood. We sequenced the genomes of five S. aureus SCV strains recovered from human patients and discovered previously unidentified...
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