Article
Influence of Plasminogen Activator Inhibitor -1 Gene Polymorphism on Renal Scarring After First Febrile Urinary Tract Infection in Infants.
Medical archives (Sarajevo, Bosnia and Herzegovina) - 1 Apr 2018
Pokrajac Danka, Kapur-Pojskic Lejla, Vegar-Zubovic Sandra, Milardovic Renata
Abstract excerpt
BACKGROUND: The pathogenesis of renal scarring (RS) after first febrile urinary tract infection (UTI) in children is multifactorial. In addition to well-known risk factors, a role for genetic predisposition has been suggested. AIMS: To determine whether deoxyribonucleic acid (DNA) polymorphisms at the plasminogen activator inhibitor -1 (PAI-1) gene were associated with evolution to RS following a febrile UTI in...
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