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Article

Rheumatic fever: from sore throat to autoimmune heart lesions.

International archives of allergy and immunology - 1 May 2004

Guilherme Luiza, Kalil Jorge

Abstract excerpt

Molecular mimicry between streptococci and heart components has been proposed as the triggering factor leading to autoimmunity in rheumatic heart disease (RHD). In this review, we present data from cellular autoimmune responses, focusing on the interactions between HLA class II molecules, streptococcal peptides and heart tissue proteins and T-cell receptor (TCR) usage. HLA-DR7DR53 associated with DQ molecules...

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Source

Identifiers

PMID: 15103230
DOI: 10.1159/000077915

Genes

RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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