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Article

Genotypic drug resistance interpretation algorithms display high levels of discordance when applied to non-B strains from HIV-1 naive and treated patients.

FEMS immunology and medical microbiology - 1 Feb 2006

Vergne Laurence, Snoeck Joke, Aghokeng Avelin, Maes Bart, Valea Diane, Delaporte Eric, Vandamme Anne-Mieke, Peeters Martine, Van Laethem Kristel

Abstract excerpt

Genotypic drug resistance interpretation algorithms have been developed on patients infected with HIV-1 subtype B to interpret complex patterns of mutations. As non-B strains are characterised by the natural presence of several resistance-related mutations, we examined to what extent this might result in interalgorithm discordances in naive and treated patients. We compared the prediction by three algorithms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16420597
DOI: 10.1111/j.1574-695X.2005.00011.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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