Article
High-resolution two-locus clonal typing of extraintestinal pathogenic Escherichia coli.
Applied and environmental microbiology - 1 Mar 2012
Weissman Scott J, Johnson James R, Tchesnokova Veronika, Billig Mariya, Dykhuizen Daniel, Riddell Kim, Rogers Peggy, Qin Xuan, Butler-Wu Susan, Cookson Brad T, Fang Ferric C, Scholes Delia, Chattopadhyay Sujay, Sokurenko Evgeni
Abstract excerpt
Multilocus sequence typing (MLST) is usually based on the sequencing of 5 to 8 housekeeping loci in the bacterial chromosome and has provided detailed descriptions of the population structure of bacterial species important to human health. However, even strains with identical MLST profiles (known as sequence types or STs) may possess distinct genotypes, which enable different eco- or pathotypic lifestyles. Here...
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